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About PERS Members UNIVDUN

University of Dundee


University of Dundee
School of Medicine, Division of Medical Sciences, Centre for Neuroscience
Centre for Child Health, 19
Dudhope Terrace
DD3 6HH Dundee
United Kingdom


Project leader

Dr David Coghill

Dr David Coghill

Phone: +44-1382 204004
Fax: +44-1382 346555

Institute presentation

Description of organisation

The University of Dundee is a leading UK institute for medical research. The Dundee Developmental Research Group (DDRG, headed up by Dr David Coghill) specializes in high quality clinical care and research into various child and adolescent neuropsychiatric disorders including ADHD, Conduct Disorder, Depression and Autism Spectrum Disorders. This group sits within the Centre for Neuroscience which includes all of the Universities’ mental health and basic neuroscience research. The Centre for Neuroscience itself is base within the Division of Medical Sciences and the School of Medicine. The DDRG conducts a wide range of research ranging from laboratory based molecular genetics and pharmacogenomics, through neuropsychology and neuropsycho-pharmacology to studies into quality of life and clinical trials. The group’s clinical research is conducted alongside the local Child and Adolescent Mental Health Services with whom we share staff and have strong links. This service receives around 1000 new referrals each year. Clinical trials are conducted within a dedicated children’s clinical trial facility that is supported by the Scottish Medicines for Children Research Network. As such, research into the efficacy and safety of medication treatment for psychiatric disorders in children and adolescents is on the priority list of research activities.

Previous experience

The UNIVDUN (Coghill) have been involved, as Principle Investigator, in many international collaborations, including multi-site international medication trials (e.g. Bangs et al, 2006, Sonuga-Barke et al 2007, Wilson et al 2006) and  large scale European observational studies (e.g. Coghill et al 2006) and neuropsychopharmacological studies (e.g. Coghill et al 2007). The Centre for Neuroscience has experience in working within FP6 Integrated Projects.

Profile of staff members

David Coghill (MB ChB MRCPsych) is child and adolescent psychiatrist, and senior lecturer in Child and Adolescent Psychiatry, at the University of Dundee and Honorary Consultant Child and Adolescent Psychiatrist in the Tayside Child and Adolescent Mental Health Service. He has been involved in several trials in children and adolescents with ADHD and Conduct Disorder and is currently the global lead investigator for two large multinational clinical trials. He is also active in genetic, neuropsychological, neuropsychopharmacological and quality of life research.

Keith Matthews (MD, PhD) is professor of psychiatry an adult psychiatrist and deputy director of the Division of Medical Sciences at the University of Dundee. He is actively involved in neuropsychological and neuropsychopharmacological studies in children and adolescents and in research into treatment resistant depression and OCD in adults.

Sarah Seth (MB ChB MRCPsych) is a child and adolescent psychiatrist and Clinical Lecturer in Child and Adolescent Psychiatry. Her areas of expertise include neuropsychology and medication research in ADHD, Oppositional Defiant Disorder and Conduct Disorder. Her doctoral thesis is on the cognitive endophenotypes of ADHD.

Helen Smith (MB ChB MRCPsych) is a forensic psychiatrist and Clinical Lecturer in Psychiatry. Her areas of expertise is in Conduct Disorder and antisocial behaviours. Her doctoral thesis is on the cognitive endophenotypes of Conduct Disorder.